SCHEMBL7905574

SCHEMBL7905574

CC(=COC(=O)Cc1ccccc1)Cc1ccc(C(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.49
TSHR P16473 1/20 0.49
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CACNA1G O43497 1/20 0.41
CACNA1H O95180 1/20 0.41
CACNA1I Q9P0X4 1/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
MAPK1 P28482 1/20 0.41
KLK7 P49862 2/20 0.40
PAM P19021 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
EPHX1 P07099 1/20 0.39
GAA P10253 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7899283 0.87 CNR2 (0.39) CNR2ALDH1A1L3MBTL1RAB9ANPC1
SCHEMBL7899286 0.87 CNR2 (0.39) CNR2ALDH1A1L3MBTL1RAB9ANPC1
SCHEMBL6568168 0.84 TDP1 (0.45) CNR2TSHRALDH1A1L3MBTL1RAB9A
SCHEMBL6568165 0.84 TDP1 (0.45) CNR2TSHRALDH1A1L3MBTL1RAB9A
SCHEMBL6566596 0.84 CNR2 (0.41) CNR2ALDH1A1RAB9ANPC1MAPK1
SCHEMBL6566598 0.84 CNR2 (0.41) CNR2ALDH1A1RAB9ANPC1MAPK1
SCHEMBL7907066 0.82 MAPT (0.41) CNR2ALDH1A1L3MBTL1CACNA1HRAB9A
SCHEMBL7907069 0.82 MAPT (0.41) CNR2ALDH1A1L3MBTL1CACNA1HRAB9A
SCHEMBL6567600 0.81 ALDH1A1 (0.47) TSHRALDH1A1L3MBTL1RAB9ANPC1
SCHEMBL6567605 0.81 ALDH1A1 (0.47) TSHRALDH1A1L3MBTL1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207857-B1 FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 2001-03-27 US claimed
US-6207857-B1 FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 2001-03-27 US disclosed
EP-0887336-A1 Precursor Compounds GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) 1998-12-30 EP disclosed