Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227790 | 0.90 | TDP1 (0.45) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL2137024 | 0.87 | TDP1 (0.42) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL4621864 | 0.86 | TDP1 (0.58) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL438113 | 0.86 | TDP1 (0.58) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL992084 | 0.86 | TDP1 (0.58) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL7564036 | 0.84 | NR1D1 (0.36) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL18145576 | 0.84 | TDP1 (0.42) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL419703 | 0.84 | TDP1 (0.42) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL19952793 | 0.83 | TDP1 (0.45) | BLMPMP22HSD17B10TDP1EYA2 | |
| SCHEMBL545038 | 0.82 | NR1D1 (0.36) | BLMPMP22TDP1EYA2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876161-B1 | CONTRAST MEDIA | NYCOMED SALUTAR INC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0876161-A2 | CONTRAST MEDIA | NYCOMED SALUTAR, INC. (US) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026921-A2 | CONTRAST MEDIA | NYCOMED SALUTAR INC. (US) | 1997-07-31 | — | — | WO | disclosed |