Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 7/20 | 0.36 |
| ▸ | RXRB | P28702 | 5/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.36 |
| ▸ | RXRG | P48443 | 4/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083423 | 0.83 | TSHR (0.41) | TP53TSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL25099089 | 0.83 | NPC1 (0.47) | TSHRHPGDALDH1A1SMN1; SMN2RARB | |
| SCHEMBL20903487 | 0.83 | LPL (0.40) | P4HBLPLLIPG | |
| SCHEMBL7906030 | 0.82 | CA1 (0.42) | ALDH1A1SMN1; SMN2CA1CA2CA9 | |
| SCHEMBL21145768 | 0.80 | LPL (0.34) | LPLLIPG | |
| SCHEMBL19905011 | 0.79 | LPL (0.44) | P4HBLPLLIPG | |
| SCHEMBL18467899 | 0.79 | LPL (0.44) | P4HBLPLLIPG | |
| SCHEMBL105188 | 0.78 | LIPG (0.56) | TP53TSHRHPGDP4HBCA1 | |
| SCHEMBL22606505 | 0.76 | LPL (0.53) | LPLLIPG | |
| SCHEMBL29049598 | 0.73 | LIPG (0.66) | P4HBRXRARXRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746172-B2 | Protein-polymer nanoassemblies and intracellular protein delivery | UNIVERSITY OF MASSACHUSETTS (US) | 2023-09-05 | — | — | US | disclosed |
| US-10913730-B2 | Heteroaryl compounds and their use as Mer inhibitors | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2021-02-09 | — | — | US | disclosed |
| US-20210017314-A1 | PROTEIN-POLYMER NANOASSEMBLIES AND INTRACELLULAR PROTEIN DELIVERY | THE UNIVERSITY OF MASSACHUSETTS | 2021-01-21 | — | — | US | disclosed |
| US-20190315716-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG-A ST CO., LTD. (KR) | 2019-10-17 | — | — | US | disclosed |
| US-6197967-B1 | CYCLIZATION OF 4-CARBOXYPHENYLBORONIC ACID WITH HYDRAZIDE DERIVATIVE; HYDROLYSIS; CATALYTIC ESTERIFICATION | CLARIANT GMBH (DE) | 2001-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913730-B2 | Heteroaryl compounds and their use as Mer inhibitors | MERTK, RET, ERBB4 | TP53 460/4885TSHR 316/4885HPGD 4439/4885 |
| US-11746172-B2 | Protein-polymer nanoassemblies and intracellular protein delivery | NUP205, PHLPP2, MSN | TP53 839/4885TSHR 3625/4885HPGD 4509/4885 |
| US-20190315716-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | MERTK, RET, ERBB4 | TP53 460/4885TSHR 316/4885HPGD 4439/4885 |
| US-20210017314-A1 | PROTEIN-POLYMER NANOASSEMBLIES AND INTRACELLULAR PROTEIN DELIVERY | NUP205, PHLPP2, MSN | TP53 839/4885TSHR 3625/4885HPGD 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.