SCHEMBL7906152

SCHEMBL7906152

CCCCCCC[CH]C(=O)NN

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.47
SOAT1 P35610 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
EP300 Q09472 1/20 0.44
KDM4E B2RXH2 2/20 0.43
TSHR P16473 1/20 0.43
TERT O14746 3/20 0.42
MAPT P10636 2/20 0.42
BLM P54132 2/20 0.42
HSD17B10 Q99714 2/20 0.42
FABP4 P15090 2/20 0.42
PTPN1 P18031 2/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4602684 0.80 FAAH (0.53) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL1416049 0.78 EP300 (0.42) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL9429318 0.78 MAPT (0.50) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL10704983 0.77 SLC6A5 (0.49) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL1415757 0.77 FAAH (0.47) FAAHEP300
SCHEMBL4921576 0.76 ASAH1 (0.43) FAAHCYP1A2CYP2C19KMT2AMEN1
SCHEMBL28967967 0.76 CNR1 (0.63) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL11316842 0.76 FAAH (0.57) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL11322157 0.76 FAAH (0.57) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL10656809 0.76 FAAH (0.57) FAAHSOAT1CYP1A2CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210933-B1 AMINO ACID SEQUENCE; FOR ADDING SIALIC ACIDS TO GLYCOPROTEINS, GLYCOLIPIDS, AND OTHER ACCEPTOR MOLECULES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2001-04-03 US disclosed
US-6096529-A FROM NEISSERIA SPECIES; FOR SYNTHESIS OF DESIRED OLIGOSACCHARIDES WITH BIOLOGICAL ACTIVITY NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2000-08-01 US disclosed
EP-0906432-A1 RECOMBINANT ALPHA-2,3-SIALYLTRANSFERASES AND THEIR USES National Research Council of Canada (CA) 1999-04-07 EP disclosed
WO-1997047749-A1 RECOMBINANT α-2,3-SIALYLTRANSFERASES AND THEIR USES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1997-12-18 WO disclosed