Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 12/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650956 | 0.82 | ESR1 (0.40) | ESR1ESR2AR | |
| SCHEMBL7912734 | 0.82 | ESR1 (0.47) | ESR1ESR2ARVDR | |
| SCHEMBL8201459 | 0.81 | HTR1A (0.43) | HTR1ABRD4 | |
| SCHEMBL347042 | 0.81 | HTR1A (0.43) | ESR1HTR1ABRD4 | |
| SCHEMBL7912692 | 0.79 | VDR (0.59) | ESR1ARVDR | |
| SCHEMBL3398525 | 0.78 | HTR1A (0.58) | HTR1ABRD4 | |
| SCHEMBL7908932 | 0.76 | HTR1A (0.40) | ESR1HTR1ABRD4 | |
| SCHEMBL25757386 | 0.75 | CYP3A4 (0.58) | HTR1ABRD4 | |
| SCHEMBL7907550 | 0.75 | HTR1A (0.39) | HTR1ABRD4 | |
| SCHEMBL25193508 | 0.75 | HTR1A (0.44) | HTR1ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187493-B1 | CHARGE GENERATING MATERIAL AND ELECTRON TRANSFER MATERIAL UNIFORMLY DISPERSED WITHIN COMPATIBLE POLYESTER BINDER; PHOTOSENSITIVITY, WEAR RESISTANCE, ADHESION TO ELECTROCONDUCTIVE SUBSTRATE | KYOCERA MITA CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0738934-A2 | Electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |