Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 3/20 | 0.39 |
| ▸ | CD14 | P08571 | 3/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347042 | 0.88 | HTR1A (0.43) | HTR1ACYP3A4SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL817162 | 0.86 | HTR1A (0.35) | HTR1ACYP3A4SMN1; SMN2ALDH1A1HTR1D | |
| SCHEMBL13130673 | 0.82 | RXRA (0.40) | CYP3A4SMN1; SMN2TLR4CD14LY96 | |
| SCHEMBL25757386 | 0.82 | CYP3A4 (0.58) | HTR1ACYP3A4SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL7907550 | 0.82 | HTR1A (0.39) | HTR1ACYP3A4SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL3398525 | 0.81 | HTR1A (0.58) | HTR1AALDH1A1BRD4KDM4EGAA | |
| SCHEMBL7906169 | 0.81 | ESR1 (0.52) | HTR1ABRD4 | |
| SCHEMBL15187966 | 0.80 | THRA (0.42) | ALDH1A1HTR1DHTR1BPOLBTLR4 | |
| SCHEMBL7908932 | 0.79 | HTR1A (0.40) | HTR1ACYP3A4SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL13964548 | 0.79 | ALDH1A1 (0.49) | HTR1ACYP3A4SMN1; SMN2ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738025-B2 | Modified polyphenol binder compositions and methods for making and using same | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2020-08-11 | — | — | US | disclosed |
| US-20170022178-A1 | MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2017-01-26 | — | — | US | disclosed |
| WO-2000024715-A1 | PIPERIDINE COMPOUNDS AND THEIR USE IN THE POPULATION CONTROL OF RODENTS AND OTHER VERTEBRATE PESTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738025-B2 | Modified polyphenol binder compositions and methods for making and using same | MYB, HLCS, KDM4C | HTR1A 2287/4885CYP3A4 2031/4885SMN1; SMN2 3628/4885 |
| US-20170022178-A1 | MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME | MYB, HLCS, KDM4C | HTR1A 2287/4885CYP3A4 2031/4885SMN1; SMN2 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.