Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.59 |
| ▸ | PDE2A | O00408 | 1/20 | 0.59 |
| ▸ | AHCY | P23526 | 2/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622588 | 0.90 | ADORA1 (0.69) | HSPA5ADORA1PDE2AAHCYADORA3 | |
| SCHEMBL14429057 | 0.88 | PDE2A (0.59) | HSPA5ADORA1PDE2AAHCYNT5E | |
| SCHEMBL7902955 | 0.88 | ADORA1 (0.58) | ADORA1ADORA3RNASEL | |
| SCHEMBL7909173 | 0.86 | ADORA1 (0.52) | HSPA5ADORA1PDE2AADORA3RNASEL | |
| SCHEMBL10431915 | 0.86 | AHCY (0.62) | HSPA5ADORA1PDE2AAHCYNT5E | |
| SCHEMBL8626012 | 0.85 | ADORA3 (0.64) | ADORA1ADORA3RNASELDOT1L | |
| SCHEMBL21999233 | 0.85 | ADORA3 (0.64) | ADORA1ADORA3RNASELDOT1L | |
| SCHEMBL12360837 | 0.85 | ADORA3 (0.64) | ADORA1ADORA3RNASELDOT1L | |
| SCHEMBL12376383 | 0.85 | ADORA3 (0.64) | ADORA1ADORA3RNASELDOT1L | |
| SCHEMBL7906331 | 0.85 | ADORA1 (0.54) | ADORA1ADORA3RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37077-E1 | Adenosine derivatives and pharmaceutical composition thereof | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-5705491-A | Adenosine deaminase inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |