Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | NNMT | P40261 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 3/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606033 | 0.91 | NNMT (0.61) | ADORA1NNMTADORA3P2RX1P2RX3 | |
| SCHEMBL7906337 | 0.86 | HSPA5 (0.62) | ADORA1ADORA3PDE2ARNASELHSPA5 | |
| SCHEMBL7902955 | 0.82 | ADORA1 (0.58) | ADORA1ADORA3RNASEL | |
| SCHEMBL21999233 | 0.81 | ADORA3 (0.64) | ADORA1ADORA3RNASELADORA2AADORA2B | |
| SCHEMBL12376383 | 0.81 | ADORA3 (0.64) | ADORA1ADORA3RNASELADORA2AADORA2B | |
| SCHEMBL8626012 | 0.81 | ADORA3 (0.64) | ADORA1ADORA3RNASELADORA2AADORA2B | |
| SCHEMBL12360837 | 0.81 | ADORA3 (0.64) | ADORA1ADORA3RNASELADORA2AADORA2B | |
| SCHEMBL7906331 | 0.81 | ADORA1 (0.54) | ADORA1ADORA3RNASELP2RX1P2RX3 | |
| SCHEMBL13269158 | 0.80 | ADORA1 (0.63) | ADORA1ADORA3P2RX1P2RX3P2RX4 | |
| SCHEMBL6223541 | 0.80 | ADORA3 (0.63) | ADORA1ADORA3RNASELADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37077-E1 | Adenosine derivatives and pharmaceutical composition thereof | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |