Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | P4HB | P07237 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl 3-Hydroxybenzoate SCHEMBL67203 | 0.84 | P4HB (0.67) | CA1CA2CA12CA9CA7 | |
| Methyl 3-Hydroxybenzoate SCHEMBL29410714 | 0.84 | P4HB (0.67) | CA1CA2CA12CA9CA7 | |
| SCHEMBL7907765 | 0.83 | CA12 (0.58) | CA1CA2CA12CA9CA7 | |
| Methyl 3-Hydroxybenzoate SCHEMBL29071792 | 0.83 | P4HB (0.65) | CA1CA2CA12CA9CA7 | |
| SCHEMBL7911577 | 0.83 | CA1 (0.80) | CA1CA2CA12CA9CA7 | |
| SCHEMBL7907753 | 0.83 | TSHR (0.50) | CA1CA2CA12CA9CA7 | |
| SCHEMBL7898874 | 0.83 | TSHR (0.50) | CA1CA2CA12CA9CA7 | |
| SCHEMBL9335427 | 0.81 | TSHR (0.62) | CA1CA2CA12CA9CA7 | |
| SCHEMBL8343397 | 0.80 | ACHE (0.48) | CA1CA2CA12CA9CA7 | |
| SCHEMBL8865622 | 0.78 | CA12 (0.56) | CA1CA2CA12CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |