Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.55 |
| ▸ | P4HB | P07237 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | FASN | P49327 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420733 | 0.91 | P4HB (0.60) | CA12CA1CA2CA9CA7 | |
| SCHEMBL2339850 | 0.87 | TSHR (0.61) | CA12CA1CA2CA9CA7 | |
| Methyl 3-Hydroxybenzoate SCHEMBL29410714 | 0.87 | P4HB (0.67) | CA12CA1CA2CA9CA7 | |
| Methyl 3-Hydroxybenzoate SCHEMBL67203 | 0.87 | P4HB (0.67) | CA12CA1CA2CA9CA7 | |
| SCHEMBL9828457 | 0.86 | CA12 (0.63) | CA12CA1CA2CA9CA7 | |
| Methyl 3-Hydroxybenzoate SCHEMBL29071792 | 0.85 | P4HB (0.65) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7906383 | 0.83 | CA1 (0.55) | CA12CA1CA2CA9CA7 | |
| SCHEMBL1772864 | 0.83 | TDP1 (0.58) | CA12CA1CA2CA9CA7 | |
| SCHEMBL9339134 | 0.83 | CLK1 (0.62) | CLK1DYRK1ADYRK1BHSD17B1HSD17B2 | |
| SCHEMBL7908137 | 0.81 | PBRM1 (0.66) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |