Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.68 |
| ▸ | PPARG | P37231 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | FABP2 | P12104 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795917 | 0.86 | PPARG (0.72) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL11218545 | 0.84 | CA2 (0.52) | PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL5794669 | 0.83 | PPARG (0.72) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL25304637 | 0.83 | PPARA (0.46) | PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL7248386 | 0.81 | PPARG (0.61) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL23582474 | 0.81 | PPARA (0.64) | PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL9996916 | 0.81 | PPARG (1.00) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL10289687 | 0.81 | PPARG (0.74) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL1009896 | 0.80 | PPARA (0.73) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL11738947 | 0.79 | PPARG (0.72) | PPARAPPARGMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214879-B1 | Allosteric inhibitors of pyruvate kinase | VIRGINIA COMMONWEALTH UNIVERSITY | 2001-04-10 | — | — | US | disclosed |