SCHEMBL7906887

SCHEMBL7906887

CO[Si](OC)(OC)C(C)Cc1cccc(OC#N)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
ACHE P22303 5/20 0.35
ADRB2 P07550 2/20 0.33
IDO1 P14902 2/20 0.33
AGXT P21549 2/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CHRM2 P08172 2/20 0.33
DHFR P00374 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603014 0.86 TAAR1 (0.40) TAAR1ACHEMAOAMAOBDHFR
SCHEMBL7914532 0.84 TAAR1 (0.43) TAAR1ACHEADRB2MAOAMAOB
SCHEMBL7917112 0.82 SLC6A4 (0.39) MAOB
SCHEMBL20350466 0.82 TAAR1 (0.49) TAAR1ACHEADRB2IDO1AGXT
SCHEMBL7917107 0.76 ALOX15 (0.43) ALDH1A1
SCHEMBL7906843 0.76 ACHE (0.34) ACHE
SCHEMBL7915041 0.74 TAAR1 (0.45) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL7917098 0.73 TAAR1 (0.30) TAAR1
SCHEMBL7916753 0.73 PDE4A (0.35) CHRM1ALDH1A1SMN1; SMN2
SCHEMBL7917089 0.72 PTGS2 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217943-B1 ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS 3M INNOVATIVE PROPERTIES COMPANY 2001-04-17 US disclosed
US-5912377-A CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-15 US disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed