Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | FNTA | P49354 | 4/20 | 0.46 |
| ▸ | FNTB | P49356 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.45 |
| ▸ | SQLE | Q14534 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907074 | 1.00 | KDM4E (0.52) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL6567588 | 0.88 | ALDH1A1 (0.63) | ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL6567589 | 0.88 | ALDH1A1 (0.63) | ALDH1A1ALOX15FNTAFNTB | |
| SCHEMBL30657825 | 0.86 | ALDH1A1 (0.58) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL6569468 | 0.86 | ALDH1A1 (0.58) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL6569471 | 0.86 | ALDH1A1 (0.58) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL7899335 | 0.79 | ALOX15 (0.49) | ALDH1A1ALOX15 | |
| SCHEMBL7606685 | 0.75 | ALDH1A1 (0.47) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL446877 | 0.75 | TSHR (0.41) | KDM4EALDH1A1ALOX15MAPT | |
| SCHEMBL31171136 | 0.74 | ALDH1A1 (0.76) | ALDH1A1ALOX15KMT2AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | claimed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | disclosed |
| EP-0887336-A1 | Precursor Compounds | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-12-30 | — | — | EP | disclosed |