Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 3/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 8/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556045 | 1.00 | PIK3CG (0.47) | PIK3CGPI4KAALPLPIK3CAPIK3R1 | |
| SCHEMBL786640 | 0.80 | PIK3CG (0.52) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL29434933 | 0.79 | ALPL (0.55) | PIK3CGPI4KAALPLPIK3CAPIK3R1 | |
| SCHEMBL110313 | 0.79 | ALPL (0.55) | PIK3CGPI4KAALPLPIK3CAPIK3R1 | |
| SCHEMBL29556110 | 0.79 | ALPL (0.55) | PIK3CGPI4KAALPLPIK3CAPIK3R1 | |
| SCHEMBL807202 | 0.77 | ALPL (0.49) | PIK3CGPI4KAALPLPIK3CAPIK3R1 | |
| SCHEMBL24576804 | 0.77 | ALPL (0.47) | ALPLAAK1 | |
| SCHEMBL9953720 | 0.76 | ALPL (0.62) | PIK3CGPI4KAALPLPIK3CAPIK3R1 | |
| SCHEMBL798868 | 0.75 | ALPL (0.45) | ALPLAAK1 | |
| SCHEMBL9960814 | 0.75 | ALPL (0.58) | ALPLAAK1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724134-B | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-113214247-A | Azaindole derivative marrow cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-08-06 | — | — | CN | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |