Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | PI4KA | P42356 | 2/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.38 |
| ▸ | MTOR | P42345 | 9/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790736 | 0.80 | PIK3CG (0.47) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL29556045 | 0.80 | PIK3CG (0.47) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL30333078 | 0.77 | ALPL (0.36) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL22574365 | 0.76 | CYP19A1 (0.36) | PIK3C3 | |
| SCHEMBL30333881 | 0.75 | PIK3CA (0.59) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL462714 | 0.75 | PIK3CA (0.59) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL29610307 | 0.75 | PIK3CA (0.59) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL12276604 | 0.74 | PIK3CD (0.41) | PIK3CGPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL15571218 | 0.74 | PRF1 (0.48) | PIK3CGPI4KAPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL1118864 | 0.71 | SHMT2 (0.33) | PIK3CGPIK3CAMTORPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |