Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136872 | 0.94 | HDAC3 (0.33) | NPC1RAB9AHDAC3HDAC1HPGD | |
| SCHEMBL4396451 | 0.79 | ALDH1A1 (0.33) | NPC1HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8741061 | 0.78 | SMN1; SMN2 (0.32) | NPC1RAB9AHDAC3HDAC1LMNA | |
| SCHEMBL9136880 | 0.74 | ALDH1A1 (0.34) | NPC1HDAC3HDAC1LMNASMN1; SMN2 | |
| SCHEMBL5051008 | 0.74 | ALDH1A1 (0.34) | HDAC3HDAC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL346020 | 0.73 | ALDH1A1 (0.33) | HDAC3HDAC1SMN1; SMN2ALDH1A1DRD2 | |
| SCHEMBL30031578 | 0.73 | ALDH1A1 (0.33) | HDAC3HDAC1SMN1; SMN2ALDH1A1DRD2 | |
| SCHEMBL900949 | 0.71 | SMN1; SMN2 (0.36) | NPC1RAB9AHDAC3LMNASMN1; SMN2 | |
| SCHEMBL2283058 | 0.71 | HPGD (0.46) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL8741120 | 0.71 | NPC1 (0.43) | NPC1RAB9AHDAC3HDAC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073421-A1 | STABILIZED PROTEIN CRYSTALS, FORMULATIONS CONTAINING THEM AND METHODS OF MAKING THEM | Altus Biologics Inc. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055310-A1 | STABILIZED PROTEIN CRYSTALS, FORMULATIONS CONTAINING THEM AND METHODS OF MAKING THEM | ALTUS BIOLOGICS INC. (US) | 1999-11-04 | — | — | WO | disclosed |