Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907438 | 0.95 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL6546670 | 0.89 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7302526 | 0.89 | AGTR1 (0.57) | PPARGAGTR1AGTR2 | |
| SCHEMBL7443225 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8736122 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7307295 | 0.85 | AGTR1 (0.60) | PPARGAGTR1AGTR2KCNH2 | |
| SCHEMBL6546048 | 0.83 | AGTR1 (0.48) | PPARGAGTR1AGTR2 | |
| SCHEMBL6545316 | 0.83 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL684076 | 0.83 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL7302538 | 0.83 | AGTR1 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545912-B1 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | claimed |