SCHEMBL7907438

SCHEMBL7907438

CCCc1nc(C(C)O)c(OC(=O)O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 8/20 0.47
AGTR2 P50052 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907474 0.95 PPARG (0.49) AGTR1AGTR2
SCHEMBL684076 0.88 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL6545316 0.88 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL6546048 0.88 AGTR1 (0.48) AGTR1AGTR2
SCHEMBL13330206 0.85 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL6545442 0.85 AGTR1 (0.52) AGTR1AGTR2
SCHEMBL3840808 0.85 AGTR1 (0.57) AGTR1AGTR2
SCHEMBL7302931 0.85 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL6545554 0.85 AGTR1 (0.57) AGTR1AGTR2
SCHEMBL7302526 0.83 AGTR1 (0.57) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545912-B1 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use SANKYO CO (JP) 2001-04-25 EP claimed