Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365853 | 0.79 | PTPRC (0.38) | PTPRCCA12CA2CA14GAA | |
| SCHEMBL15340973 | 0.78 | MAOA (0.41) | ALDH1A1PTPRCCA12CA2CA14 | |
| SCHEMBL6610608 | 0.76 | MEN1 (0.41) | PTPRCCA12CA2CA14GAA | |
| SCHEMBL410255 | 0.76 | CA2 (0.40) | PTPRCCA12CA2CA14CA1 | |
| SCHEMBL14056719 | 0.76 | PTPRC (0.36) | PTPRCCA12CA2CA14GAA | |
| Hydrochloric Acid SCHEMBL219630 | 0.74 | CA2 (0.39) | PTPRCCA12CA2CA14CA1 | |
| SCHEMBL6937980 | 0.74 | MEN1 (0.40) | PTPRCCA12CA2CA14GAA | |
| SCHEMBL7660758 | 0.74 | PTPRC (0.40) | LMNAPTPRCCA12CA2CA14 | |
| Hydrochloric Acid SCHEMBL31480795 | 0.74 | CA2 (0.39) | PTPRCCA12CA2CA14CA1 | |
| SCHEMBL125503 | 0.74 | TDP1 (0.52) | ALDH1A1CA12CA2CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288093-B1 | COMPOUNDS SUCH AS (6-CHLORO-3-METHYL-3,8-DIHYDROINDENO (1,2-D)THIAZOL-2-YLIDENE)METHYLAMINE HYDROBROMIDE USED AS ANORECTICS AND ANTIDIABETICS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6288094-B2 | COMPOUNDS SUCH AS (6-CHLORO-3-METHYL-3,8-DIHYDROINDENO (1,2-D)THIAZOL-2-YLIDENE)METHYLAMINE HYDROBROMIDE USED AS ANORECTICS AND ANTIDIABETICS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-09-11 | — | — | US | disclosed |
| US-20010011096-A1 | Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2001-08-02 | — | — | US | disclosed |
| US-6207689-B1 | AS ANORECTICS AND IN THE TREATMENT OR PROPHYLAXIS OF TYPE II DIABETES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011096-A1 | Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments | SLC5A2, OTC, GOT2 | ALDH1A1 289/4885LMNA 2551/4885PTPRC 2665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.