Pyridine

Pyridine

SCHEMBL7907613

O=C(Cl)Oc1ccccc1[N+](=O)[O-].c1ccncc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
ALDH1A1 P00352 6/20 0.49
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
RAB9A P51151 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
HPGD P15428 1/20 0.45
NPC1 O15118 1/20 0.45
RECQL P46063 1/20 0.45
KDM4E B2RXH2 3/20 0.44
ESR2 Q92731 1/20 0.44
HTT P42858 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
POLB P06746 2/20 0.43
KCNH2 Q12809 1/20 0.43
GAA P10253 1/20 0.43
NCOA1 Q15788 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31283123 0.89 ALDH1A1 (0.56) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL223281 0.89 ALDH1A1 (0.56) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
Methane SCHEMBL7272152 0.88 ALDH1A1 (0.55) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL57737 0.77 ALDH1A1 (0.58) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL57738 0.77 ALDH1A1 (0.58) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
Pyridine SCHEMBL3710082 0.77 HTT (0.56) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
Pyridine SCHEMBL11046519 0.77 ALDH1A1 (0.52) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
Bicarbonate SCHEMBL18955378 0.76 ALDH1A1 (0.56) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
Bicarbonate SCHEMBL18955379 0.76 ALDH1A1 (0.56) MAPTCYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL57736 0.76 ALDH1A1 (0.60) MAPTCYP1A2CYP2C9ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082105-A1 CONTROLLED DRUG DELIVERY SYSTEM USING THE CONJUGATION OF DRUG TO BIODEGRADABLE POLYESTER MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) 2001-03-14 EP disclosed
WO-1999059548-A1 CONTROLLED DRUG DELIVERY SYSTEM USING THE CONJUGATION OF DRUG TO BIODEGRADABLE POLYESTER MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) 1999-11-25 WO disclosed