Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223281 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL31283123 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| Pyridine SCHEMBL7907613 | 0.88 | MAPT (0.59) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL29911025 | 0.83 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL28793663 | 0.83 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL31572517 | 0.83 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL57736 | 0.83 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL430044 | 0.83 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL1652615 | 0.83 | GPR35 (0.51) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL9615027 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1RAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180111-A4 | METHOD AND APPARATUS FOR COMPOUND LIBRARY PREPARATION USING OPTICAL MODULATOR | MACROGEN INC (KR) | 2003-03-26 | — | — | EP | disclosed |
| EP-1180111-A1 | METHOD AND APPARATUS FOR COMPOUND LIBRARY PREPARATION USING OPTICAL MODULATOR | Macrogen Inc. (KR) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000047598-A1 | METHOD AND APPARATUS FOR COMPOUND LIBRARY PREPARATION USING OPTICAL MODULATOR | MACROGEN INC. (KR) | 2000-08-17 | — | — | WO | disclosed |