Sugi Predict

Sugi Predict / Compounds / SCHEMBL223281

SCHEMBL223281

SCHEMBL223281

O=C(Cl)Oc1ccccc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ RAB9A P51151 2/20 0.55
▸ NPC1 O15118 1/20 0.55
▸ RECQL P46063 1/20 0.55
▸ L3MBTL1 Q9Y468 2/20 0.54
▸ HPGD P15428 1/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ MAPT P10636 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ HTT P42858 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ KDM4E B2RXH2 2/20 0.50
▸ ESR2 Q92731 1/20 0.48
▸ POLB P06746 3/20 0.47
▸ KCNH2 Q12809 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ SENP8 Q96LD8 1/20 0.44
▸ SENP7 Q9BQF6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31283123 1.00 ALDH1A1 (0.56) ALDH1A1TDP1RAB9ANPC1RECQL
Methane SCHEMBL7272152 0.98 ALDH1A1 (0.55) ALDH1A1TDP1RAB9ANPC1RECQL
Pyridine SCHEMBL7907613 0.89 MAPT (0.59) ALDH1A1TDP1RAB9ANPC1RECQL
SCHEMBL29911025 0.85 ALDH1A1 (0.60) ALDH1A1TDP1RAB9ANPC1RECQL
SCHEMBL28793663 0.85 ALDH1A1 (0.60) ALDH1A1TDP1RAB9ANPC1RECQL
SCHEMBL31572517 0.85 ALDH1A1 (0.60) ALDH1A1TDP1RAB9ANPC1RECQL
SCHEMBL57736 0.85 ALDH1A1 (0.60) ALDH1A1TDP1RAB9ANPC1RECQL
SCHEMBL430044 0.85 ALDH1A1 (0.60) ALDH1A1TDP1RAB9ANPC1RECQL
SCHEMBL1652615 0.84 GPR35 (0.51) ALDH1A1TDP1RAB9ANPC1RECQL
SCHEMBL9615027 0.84 ALDH1A1 (0.55) ALDH1A1TDP1RAB9ANPC1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1829 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241445-A Method for preparing dapest by one-pot method 武汉工程大学 2025-01-03 — — CN claimed
CN-115925746-B Porphyrin-based reducible and degradable fluorine-containing surfactant and preparation and application thereof 中山大学 2024-04-12 — — CN claimed
CN-114605436-B Intermediate of Pa Luo Weide or boceprevir, preparation method and application 浙江九洲药业股份有限公司 2023-07-21 — — CN claimed
US-11692215-B2 Nucleic acid cleaving enzyme-based biosensor and methods of use thereof MCMASTER UNIVERSITY (CA) 2023-07-04 — — US claimed
CN-115925746-A Porphyrin-based reducible and degradable fluorine-containing surfactant and preparation and application thereof 中山大学 2023-04-07 — — CN claimed
CN-110893172-B Elemene polymer micelle preparation and preparation method and application thereof 四川省人民医院 2022-07-08 — — CN claimed
EP-3582784-B1 PROCESSES FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES ENANTA PHARM INC (US) 2022-06-08 — — EP claimed
CN-111974231-B Preparation method of surface-modified anti-pollution nanofiltration membrane 启成（江苏）净化科技有限公司 2022-01-28 — — CN claimed
CN-110272539-B Ligand conjugate and probe for binding PMSA (PMSA), and preparation method and application thereof 广东工业大学 2021-09-17 — — CN claimed
US-10906895-B2 Processes for the preparation of benzodiazepine derivatives ENANTA PHARMACEUTICALS, INC. (US) 2021-02-02 — — US claimed
WO-2006003329-A1 COLLECTION OF TRACEABLE COMPOUNDS AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2006-01-12 — — WO claimed
WO-2000061545-A1 METHODS FOR SOLID PHASE COMBINATORIAL SYNTHESIS OF INTEGRIN INHIBITORS AMERICAN HOME PRODUCTS CORPORATION (US) 2000-10-19 — — WO claimed
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 — — EP claimed
WO-1999011202-A1 BIOMIMETIC CALCIUM PHOSPHATE IMPLANT COATINGS AND METHODS FOR MAKING THE SAME ICET, INC. (US) 1999-03-11 — — WO claimed
US-5773625-A Process for the preparation of disubstituted carbonates ABBOTT LABORATORIES (US) 1998-06-30 — — US claimed
WO-1994005332-A2 GLYCOLATION OF GLYCOSYLATED MACROMOLECULES BERLEX LABORATORIES, INC. (US) 1994-03-17 — — WO claimed
CN-1067431-A Amidinophenylalaninederivatives derivatives, their preparation method, their application and contain their composition BEHRINGWERKE AG (DE) 1992-12-30 — — CN claimed
WO-1990007938-A1 PREPARATION OF A POLYMER/INTERLEUKIN-2 CONJUGATE CETUS CORPORATION (US) 1990-07-26 — — WO claimed
US-4902502-A Preparation of a polymer/interleukin-2 conjugate CETUS CORPORATION (US) 1990-02-20 — — US claimed
EP-0309406-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1989-03-29 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10906895-B2 Processes for the preparation of benzodiazepine derivatives CYP11B1, CYP11B2, CYP3A5 ALDH1A1 446/4885TDP1 3788/4885RAB9A 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.