Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964613 | 0.92 | CES2 (0.47) | ESR1ESR2PTGS2CYP1B1KDM4E | |
| Anthracene SCHEMBL5666379 | 0.87 | CYP19A1 (0.53) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL10324912 | 0.85 | ESR1 (0.41) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL19639003 | 0.85 | CYP19A1 (0.42) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL13084922 | 0.84 | PTPN1 (0.51) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL14077407 | 0.83 | PTGS2 (0.45) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL13508382 | 0.83 | ESR1 (0.45) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL2085352 | 0.82 | CYP19A1 (0.42) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL13085260 | 0.82 | CA1 (0.50) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL10646653 | 0.81 | RELA (0.53) | ESR1CYP19A1CYP11B2PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6198217-B1 | Organic electroluminescent device having a protective covering comprising organic and inorganic layers | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |