Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16167678 | 0.84 | AVPR2 (0.43) | AVPR2AVPR1AMEN1KMT2AMGLL | |
| SCHEMBL8739503 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1AMEN1KMT2ACCR2 | |
| SCHEMBL4499296 | 0.79 | AVPR2 (0.55) | AVPR2AVPR1ATP53 | |
| SCHEMBL2513250 | 0.79 | AVPR2 (0.50) | AVPR2AVPR1AMEN1KMT2ACCR2 | |
| SCHEMBL8233125 | 0.78 | AVPR2 (0.53) | AVPR2AVPR1AMEN1KMT2ATRPV4 | |
| SCHEMBL7913159 | 0.75 | LMNA (0.43) | MEN1KMT2A | |
| SCHEMBL7916915 | 0.73 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL463144 | 0.73 | AVPR2 (0.55) | AVPR2AVPR1ATP53 | |
| SCHEMBL719285 | 0.72 | AVPR2 (0.53) | AVPR2AVPR1ATP53 | |
| SCHEMBL8232662 | 0.72 | AVPR2 (0.46) | AVPR2AVPR1AMGLLTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063402-A1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |