Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542302 | 0.81 | LMNA (0.42) | LMNAMAPTHSD17B10TSHRNPC1 | |
| SCHEMBL16167676 | 0.80 | ALDH1A1 (0.47) | LMNAMAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL3976537 | 0.75 | LMNA (0.44) | LMNAMAPTTSHRNPC1RAB9A | |
| SCHEMBL8228870 | 0.75 | TSHR (0.58) | LMNAHSD17B10TSHRNPC1RAB9A | |
| SCHEMBL7913999 | 0.74 | ALDH1A1 (0.42) | LMNAMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL4506900 | 0.73 | LMNA (0.44) | LMNAMAPTHSD17B10TSHRNPC1 | |
| SCHEMBL4491713 | 0.72 | TSHR (0.54) | LMNAMAPTHSD17B10TSHRNPC1 | |
| SCHEMBL7916915 | 0.70 | HSD11B1 (0.40) | LMNASMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL4499313 | 0.70 | KDM4E (0.43) | LMNAHSD17B10TSHRUSP2MEN1 | |
| SCHEMBL7480159 | 0.70 | CA12 (0.61) | LMNAMAPTHSD17B10TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063402-A1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |