Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816495 | 0.82 | ALDH1A1 (0.84) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL6815396 | 0.80 | ALDH1A1 (0.64) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL17956801 | 0.79 | ALDH1A1 (0.68) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL7908225 | 0.79 | MEN1 (0.49) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL6815404 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL10242286 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL6814864 | 0.77 | KMT2A (0.58) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL1514611 | 0.75 | ALOX15 (0.61) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL6811642 | 0.74 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EPOLBKMT2A | |
| SCHEMBL16566479 | 0.73 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |