Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816499 | 0.84 | ALDH1A1 (0.53) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6814866 | 0.80 | KMT2A (0.52) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7908221 | 0.79 | ALDH1A1 (0.67) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6815400 | 0.78 | LMNA (0.49) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7640628 | 0.74 | MAPT (0.48) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6819363 | 0.71 | KMT2A (0.56) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6814833 | 0.70 | RAB9A (0.46) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6815262 | 0.69 | CYP3A4 (0.49) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL2008072 | 0.68 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL11539501 | 0.68 | MEN1 (0.54) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |