Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392066 | 0.86 | HSP90AA1 (0.46) | HSP90AA1HCAR2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL11162398 | 0.78 | HSP90AA1 (0.45) | HSP90AA1HCAR2ALDH1A1LMNA | |
| SCHEMBL9374946 | 0.77 | HSP90AA1 (0.47) | HSP90AA1ALDH1A1L3MBTL1TSHRPOLB | |
| SCHEMBL12305771 | 0.77 | HSP90AA1 (0.50) | HSP90AA1HCAR2ALDH1A1TSHRPOLB | |
| SCHEMBL12305754 | 0.77 | HSP90AA1 (0.50) | HSP90AA1HCAR2ALDH1A1TSHRPOLB | |
| SCHEMBL9094 | 0.77 | HSP90AA1 (0.50) | HSP90AA1HCAR2ALDH1A1TSHRPOLB | |
| SCHEMBL2597946 | 0.75 | ALDH1A1 (0.49) | HSP90AA1ALDH1A1TSHRPOLBLMNA | |
| SCHEMBL7368845 | 0.74 | POLB (0.43) | HSP90AA1ALDH1A1L3MBTL1TSHRPOLB | |
| SCHEMBL1508 | 0.74 | HSP90AA1 (0.55) | HSP90AA1ALDH1A1L3MBTL1TSHRPOLB | |
| SCHEMBL13908046 | 0.74 | HSP90AA1 (0.47) | HSP90AA1ALDH1A1TSHRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211397-B1 | CHLORINATION OF PHOSPHORANES | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | disclosed |