Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392066 | 0.77 | HSP90AA1 (0.46) | HSP90AA1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7908281 | 0.74 | HSP90AA1 (0.44) | POLBHSP90AA1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2392064 | 0.74 | LMNA (0.50) | POLBHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL65066 | 0.73 | HSP90AA1 (0.50) | POLBHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL27988558 | 0.72 | LMNA (0.51) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL6879691 | 0.72 | HSP90AA1 (0.49) | POLBHSP90AA1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9061399 | 0.72 | HSP90AA1 (0.49) | POLBHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL11162398 | 0.72 | HSP90AA1 (0.45) | HSP90AA1ALDH1A1KMT2A | |
| SCHEMBL852873 | 0.72 | TSHR (0.50) | HSP90AA1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7361452 | 0.71 | GPR52 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871439-A4 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0871439-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024117-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |