Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962253 | 0.91 | MAOB (0.61) | MAOBNPC1FFAR4 | |
| SCHEMBL7907439 | 0.89 | MAOB (0.56) | MRGPRX4MAOBNPC1FFAR4 | |
| SCHEMBL7901056 | 0.87 | MRGPRX4 (0.61) | ALOX5MRGPRX4MAOBNPC1MAPT | |
| SCHEMBL7910727 | 0.87 | RXRA (0.54) | ALOX5MRGPRX4MAOBNPC1FFAR4 | |
| SCHEMBL7911112 | 0.86 | MAOB (0.57) | MAOBNPC1FFAR4MAOA | |
| SCHEMBL7910948 | 0.86 | MAOB (0.57) | MAOBNPC1FFAR4MAOA | |
| SCHEMBL7910894 | 0.86 | FFAR4 (0.65) | MRGPRX4MAOBMAPTFFAR4MAOA | |
| SCHEMBL7908741 | 0.86 | MAOB (0.56) | ALOX5MRGPRX4MAOBNPC1MAPT | |
| SCHEMBL21924287 | 0.86 | MAOB (0.58) | MAOBNPC1MAPTFFAR4 | |
| SCHEMBL7787014 | 0.86 | CAPN1 (0.57) | NPC1MAPTFFAR4CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |