Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962253 | 0.89 | MAOB (0.61) | MAOBKMT2AMEN1ALDH1A1FFAR4 | |
| SCHEMBL7900845 | 0.88 | NR4A2 (0.51) | MAOBKMT2AMETMEN1ALDH1A1 | |
| SCHEMBL7909189 | 0.87 | MAOB (0.53) | MAOBKMT2AMEN1ALDH1A1GPR132 | |
| SCHEMBL3191667 | 0.86 | MAOB (0.58) | MAOBKMT2AMEN1ALDH1A1FFAR4 | |
| SCHEMBL7907439 | 0.84 | MAOB (0.56) | MAOBALDH1A1FFAR4KDM4ENPC1 | |
| SCHEMBL21924287 | 0.84 | MAOB (0.58) | MAOBKMT2AMEN1ALDH1A1FFAR4 | |
| SCHEMBL16485525 | 0.83 | PARP10 (0.54) | KMT2ASYKMEN1ALDH1A1AURKB | |
| SCHEMBL1763456 | 0.83 | MAOB (0.57) | MAOBKMT2AMEN1ALDH1A1FFAR4 | |
| SCHEMBL3201763 | 0.83 | MAOB (0.57) | MAOBKMT2AMEN1ALDH1A1FFAR4 | |
| SCHEMBL11557673 | 0.82 | KDM4E (0.60) | MAOBKMT2AMEN1FFAR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |