Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962253 | 0.92 | MAOB (0.61) | MAOBFFAR4MEN1KMT2AALDH1A1 | |
| SCHEMBL7907439 | 0.87 | MAOB (0.56) | MAOBFFAR4ALDH1A1NPC1RAB9A | |
| SCHEMBL7914070 | 0.87 | MAOB (0.55) | MAOBNOX1GPR132MEN1KMT2A | |
| SCHEMBL21924287 | 0.87 | MAOB (0.58) | MAOBFFAR4MEN1KMT2AALDH1A1 | |
| SCHEMBL3191667 | 0.87 | MAOB (0.58) | MAOBFFAR4MEN1KMT2AALDH1A1 | |
| SCHEMBL7908699 | 0.87 | MAOB (0.50) | MAOBFFAR4GPR132MEN1KMT2A | |
| SCHEMBL3201763 | 0.86 | MAOB (0.57) | MAOBFFAR4MEN1KMT2AALDH1A1 | |
| SCHEMBL1763456 | 0.86 | MAOB (0.57) | MAOBFFAR4MEN1KMT2AALDH1A1 | |
| SCHEMBL11557673 | 0.85 | KDM4E (0.60) | MAOBFFAR4LRRK2MEN1KMT2A | |
| SCHEMBL7910894 | 0.85 | FFAR4 (0.65) | MAOBFFAR4KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |