Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556012 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL4462187 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL3848317 | 0.75 | HTT (0.40) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL372527 | 0.73 | CHAT (0.61) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL11386724 | 0.69 | RAB9A (0.51) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL11386719 | 0.69 | RAB9A (0.51) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| Phenol SCHEMBL9390292 | 0.67 | CA12 (0.46) | ALDH1A1KDM4EHTTPTGS2MAPT | |
| SCHEMBL3341816 | 0.67 | PTGS2 (0.40) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL10398844 | 0.67 | PPARG (0.43) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL10418852 | 0.67 | GAA (0.52) | ALDH1A1MEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6289027-B1 | Fiber optic lasers employing fiber optic amplifiers | MOLECULAR OPTOELECTRONICS CORPORATION | 2001-09-11 | — | — | US | claimed |
| US-6198569-B1 | Multiple window dense wavelength divison multiplexed communications link with optical amplification and dispersion compensation | MOLECULAR OPTOELECTRONICS CORPORATION | 2001-03-06 | — | — | US | claimed |
| WO-1999043058-A1 | FIBER OPTIC LASERS EMPLOYING FIBER OPTIC AMPLIFIERS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1999-08-26 | — | — | WO | claimed |
| WO-1999043121-A2 | COMMUNICATIONS LINK OPTICAL AMPLIFICATION AND DISPERSION COMPENSATION | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1999-08-26 | — | — | WO | claimed |
| US-5815309-A | Optical amplifier and process for amplifying an optical signal propagating in a fiber optic | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1998-09-29 | — | — | US | claimed |
| WO-1998032048-A1 | OPTICAL WAVEGUIDE AMPLIFIER | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1998-07-23 | — | — | WO | claimed |
| US-5396362-A | High resolution micromachining of organic crystals and optical modulators formed thereby | GENERAL ELECTRIC COMPANY (US) | 1995-03-07 | — | — | US | claimed |
| US-6289027-B1 | Fiber optic lasers employing fiber optic amplifiers | MOLECULAR OPTOELECTRONICS CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-6198569-B1 | Multiple window dense wavelength divison multiplexed communications link with optical amplification and dispersion compensation | MOLECULAR OPTOELECTRONICS CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6052220-A | Optical amplifier and process for amplifying an optical signal propagating in a fiber optic employing an overlay waveguide and stimulated emission | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |
| WO-1999043057-A1 | OPTICAL AMPLIFIER AND PROCESS FOR AMPLIFYING AN OPTICAL SIGNAL PROPAGATING IN A FIBER OPTIC EMPLOYING AN OVERLAY WAVEGUIDE AND STIMULATED EMISSION | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1999-08-26 | — | — | WO | disclosed |
| WO-1999043058-A1 | FIBER OPTIC LASERS EMPLOYING FIBER OPTIC AMPLIFIERS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1999-08-26 | — | — | WO | disclosed |
| WO-1999043121-A2 | COMMUNICATIONS LINK OPTICAL AMPLIFICATION AND DISPERSION COMPENSATION | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1999-08-26 | — | — | WO | disclosed |
| EP-0914698-A1 | OPTICAL WAVEGUIDE AMPLIFIER | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1999-05-12 | — | — | EP | disclosed |
| US-5815309-A | Optical amplifier and process for amplifying an optical signal propagating in a fiber optic | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1998-09-29 | — | — | US | disclosed |
| WO-1998032199-A1 | OPTICAL WAVEGUIDE AMPLIFIER | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1998-07-23 | — | — | WO | disclosed |
| WO-1998032048-A1 | OPTICAL WAVEGUIDE AMPLIFIER | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1998-07-23 | — | — | WO | disclosed |