Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909440 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BITGA2CHRM3GAA | |
| SCHEMBL7909451 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BITGA2CHRM3GAA | |
| SCHEMBL7909845 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BITGA2CHRM3GAA | |
| SCHEMBL7900157 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BITGA2CHRM3GAA | |
| Hydrochloric Acid SCHEMBL7909753 | 0.83 | POLB (0.57) | ITGB3ITGA2BITGA2CHRM3GAA | |
| SCHEMBL7900164 | 0.83 | MEN1 (0.50) | ITGB3ITGA2BITGA2GAAPOLB | |
| SCHEMBL8381170 | 0.80 | CHRM3 (0.49) | CHRM3POLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7909796 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2BITGA2CHRM3GAA | |
| SCHEMBL9335419 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BITGA2GAAALDH1A1 | |
| SCHEMBL8382626 | 0.79 | EPHX2 (0.48) | ITGB3ITGA2BITGA2CHRM3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608759-B1 | Piperazine derivatives | MERCK PATENT GMBH (DE) | 2001-08-22 | — | — | EP | disclosed |
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |
| EP-0608759-A2 | Piperazinderivatives | MERCK PATENT GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |