Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | PLAT | P00750 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791124 | 0.84 | APP (0.46) | MAPK1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL790416 | 0.80 | MRGPRX4 (0.50) | ALDH1A1MEN1LMNATSHRKMT2A | |
| SCHEMBL31544096 | 0.77 | KMT2A (0.55) | ALDH1A1KDM4EHPGDMEN1LMNA | |
| SCHEMBL23756529 | 0.77 | VNN1 (0.47) | ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL31544102 | 0.77 | TP53 (0.49) | KMT2ACA1CA2 | |
| SCHEMBL29523642 | 0.77 | APP (0.55) | MAPK1ALDH1A1CLK4MEN1USP2 | |
| SCHEMBL790421 | 0.77 | APP (0.42) | FYNCYP11B1CYP11B2ALDH1A1CLK4 | |
| SCHEMBL789699 | 0.76 | HTT (0.56) | MAPK1SMN1; SMN2CLK4MEN1KMT2A | |
| SCHEMBL789612 | 0.76 | MEN1 (0.44) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL31544214 | 0.76 | MAPT (0.45) | KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |