Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790421 | 0.88 | APP (0.42) | APPCLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL790949 | 0.84 | PLAU (0.44) | CLK4MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29523642 | 0.80 | APP (0.55) | APPCLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL789699 | 0.79 | HTT (0.56) | APPCLK4MEN1KMT2AMAPK1 | |
| SCHEMBL789612 | 0.79 | MEN1 (0.44) | APPMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL791199 | 0.78 | RAB9A (0.50) | APPLMNAACP1RAB9ADYRK1A | |
| SCHEMBL790131 | 0.73 | PIK3CD (0.56) | — | |
| SCHEMBL18571730 | 0.72 | MEN1 (0.44) | APPMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL21061514 | 0.72 | EGFR (0.51) | APPMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL789801 | 0.72 | HTT (0.45) | APPMEN1KMT2ALMNAACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |