Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789915 | 0.88 | RAB9A (0.50) | KDRRAB9AMEN1KMT2ALMNA | |
| SCHEMBL791199 | 0.87 | RAB9A (0.50) | KDRRAB9APIK3CASTAT6LMNA | |
| SCHEMBL790392 | 0.85 | KDR (0.48) | KDRRAB9ALMNAMAPTLRRK2 | |
| SCHEMBL790093 | 0.85 | SMN1; SMN2 (0.48) | KDRRAB9AMEN1KMT2APIK3CA | |
| SCHEMBL790646 | 0.85 | KDR (0.47) | KDRRAB9AMEN1KMT2ASTAT6 | |
| SCHEMBL791145 | 0.83 | KDR (0.46) | KDRRAB9AMEN1KMT2APIK3CA | |
| SCHEMBL789889 | 0.81 | RAB9A (0.48) | KDRRAB9APIK3CASTAT6PTGDR | |
| SCHEMBL789670 | 0.81 | PI4KA (0.51) | MRGPRX4RAB9AMEN1KMT2APIK3CA | |
| SCHEMBL790949 | 0.80 | PLAU (0.44) | MEN1KMT2ALMNATSHRPTGDR | |
| SCHEMBL790621 | 0.79 | KDR (0.46) | KDRRAB9AMEN1KMT2ASTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |