Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429197 | 0.89 | HTR3E (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7929303 | 0.82 | KDR (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7916930 | 0.74 | KIF11 (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL979367 | 0.73 | CLCN2 (0.47) | ALDH1A1KDRCLCN2NOTUMTYK2 | |
| SCHEMBL7926464 | 0.73 | KDR (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4941062 | 0.72 | NPFFR2 (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL16088888 | 0.72 | NPFFR2 (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7920531 | 0.71 | HTR3E (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7574925 | 0.71 | HTR3E (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6571700 | 0.70 | RORB (0.36) | ALDH1A1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10053573-A | — | — | None | — | — | JP | disclosed |
| US-6211232-B1 | REACTION OF BENZONITRILE WITH HYDROXYLAMINE IN THE PRESENCE OF CHELATION AGENT | NIPPON SODA CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| JP-H1053573-A | PRODUCTION OF 2,3-DIHALOGENO-6-TRIFLUOROMETHYL BENZAMIDOXIME | NIPPON SODA CO LTD | 1998-02-24 | — | — | JP | disclosed |