Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 15/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160325 | 0.88 | GRM2 (0.62) | GRM2MAPK1L3MBTL1HRH3HTR2B | |
| SCHEMBL24933695 | 0.86 | GRM2 (0.51) | GRM2MAPK1L3MBTL1HRH3HTR2B | |
| SCHEMBL11161832 | 0.84 | GRM2 (0.50) | GRM2MAPK1L3MBTL1HRH3HTR2B | |
| SCHEMBL7909523 | 0.84 | GRM2 (0.49) | GRM2MAPK1L3MBTL1HRH3HTR2B | |
| SCHEMBL11875374 | 0.83 | HTR2B (0.47) | GRM2MAPK1L3MBTL1HRH3HTR2B | |
| SCHEMBL9636582 | 0.81 | GRM2 (0.47) | GRM2MAPK1L3MBTL1HTR2BTDP1 | |
| SCHEMBL9636573 | 0.81 | GRM2 (0.47) | GRM2MAPK1L3MBTL1HTR2BTDP1 | |
| SCHEMBL9752599 | 0.81 | LMNA (0.51) | GRM2MAPK1L3MBTL1HTR2B | |
| SCHEMBL11154145 | 0.81 | GRM2 (0.46) | GRM2MAPK1L3MBTL1HTR2B | |
| SCHEMBL7911772 | 0.80 | HTR2B (0.50) | GRM2MAPK1L3MBTL1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061366-A1 | MANUFACTURE OF BISOPROLOL AND INTERMEDIATES THEREFOR | CORDEN PHARMA IP LIMITED (IE) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010061366-A1 | MANUFACTURE OF BISOPROLOL AND INTERMEDIATES THEREFOR | CORDEN PHARMA IP LIMITED (IE) | 2010-06-03 | — | — | WO | disclosed |
| EP-0086403-A2 | 2-Oxazolidine-ones | MERCK PATENT GmbH (DE) | 1983-08-24 | — | — | EP | disclosed |