Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510772 | 0.74 | — | — | |
| Trichloroethane SCHEMBL28474125 | 0.68 | GRIN2D (0.31) | — | |
| SCHEMBL3391901 | 0.68 | — | — | |
| SCHEMBL6562524 | 0.67 | CYP1A2 (0.39) | OPRL1TSHR | |
| SCHEMBL28677213 | 0.64 | TSHR (0.41) | OPRL1POLBTSHR | |
| SCHEMBL7169862 | 0.61 | MEN1 (0.33) | POLBTSHR | |
| SCHEMBL30968185 | 0.61 | — | — | |
| SCHEMBL28373094 | 0.60 | CALM1 (0.38) | OPRL1POLBTSHR | |
| SCHEMBL23888569 | 0.58 | MEN1 (0.41) | OPRL1POLB | |
| SCHEMBL7200662 | 0.56 | HDAC4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225352-B1 | USEFUL AS AGENTS IN THE TREATMENT OF CANCER, ALZHEIMERS DISEASE, THROMBOSIS, INFLAMMATORY DISEASES, AND BACTERIAL RESISTANCE | WARNER-LAMBERT COMPANY | 2001-05-01 | — | — | US | disclosed |
| WO-1998006691-A2 | LOW MOLECULAR WEIGHT DENDRITIC COMPOUNDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |