⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391901 | 0.77 | — | — | |
| SCHEMBL7169862 | 0.73 | MEN1 (0.33) | — | |
| SCHEMBL10823141 | 0.71 | OPRL1 (0.34) | — | |
| SCHEMBL11265347 | 0.70 | MAOB (0.31) | — | |
| SCHEMBL5552788 | 0.70 | CALM1 (0.32) | — | |
| SCHEMBL6422591 | 0.66 | — | — | |
| SCHEMBL7909638 | 0.61 | OPRL1 (0.33) | — | |
| SCHEMBL27999891 | 0.58 | HDAC4 (0.32) | — | |
| SCHEMBL3890069 | 0.57 | MAOA (0.60) | — | |
| SCHEMBL14559518 | 0.57 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353863-A1 | TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY | INST NAT SANTE RECH MED (FR) | 2025-11-20 | — | — | US | disclosed |
| CN-118344586-A | Ion covalent organic polymer material and preparation method and application thereof | 河北工程大学 | 2024-07-16 | — | — | CN | disclosed |