Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 9/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917510 | 0.81 | MEN1 (0.34) | — | |
| SCHEMBL7919693 | 0.81 | MEN1 (0.34) | — | |
| SCHEMBL7916983 | 0.81 | CYP3A4 (0.34) | MDM2 | |
| SCHEMBL7917015 | 0.78 | DRD4 (0.32) | SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL7919224 | 0.77 | MEN1 (0.33) | SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL7838454 | 0.76 | MEN1 (0.54) | L3MBTL1 | |
| SCHEMBL7922600 | 0.76 | MEN1 (0.32) | SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL7919228 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL7919391 | 0.73 | NPSR1 (0.38) | L3MBTL1 | |
| SCHEMBL7919720 | 0.72 | L3MBTL1 (0.44) | SLC6A2SLC6A4SLC6A3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |