Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912979 | 0.88 | EEF2K (0.39) | SLC9A1ALDH1A1LMNAMAPK1HTT | |
| SCHEMBL7902995 | 0.82 | SLC9A1 (0.38) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL11648888 | 0.80 | SMN1; SMN2 (0.49) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL7916794 | 0.79 | SLC9A1 (0.61) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL927183 | 0.79 | SLC9A1 (0.45) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL927184 | 0.79 | SLC9A1 (0.61) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL7916809 | 0.79 | SLC9A1 (0.45) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL7912931 | 0.78 | SLC9A1 (0.59) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL926631 | 0.77 | SLC9A1 (0.43) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL7913104 | 0.76 | KDM4E (0.45) | SLC9A1SMN1; SMN2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |