Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910258 | 0.88 | SLC9A1 (0.41) | EEF2KSLC9A1ALDH1A1MEN1NPC1 | |
| SCHEMBL7902995 | 0.78 | SLC9A1 (0.38) | EEF2KSLC9A1ALDH1A1NPC1RAB9A | |
| SCHEMBL7902812 | 0.78 | ALDH1A1 (0.39) | SLC9A1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL7916809 | 0.77 | SLC9A1 (0.45) | EEF2KSLC9A1ALDH1A1NPC1RAB9A | |
| SCHEMBL7911271 | 0.76 | KDM4E (0.57) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7916794 | 0.75 | SLC9A1 (0.61) | EEF2KSLC9A1ALDH1A1NPC1RAB9A | |
| SCHEMBL927183 | 0.75 | SLC9A1 (0.45) | EEF2KSLC9A1ALDH1A1MEN1NPC1 | |
| SCHEMBL927184 | 0.75 | SLC9A1 (0.61) | EEF2KSLC9A1ALDH1A1NPC1RAB9A | |
| SCHEMBL7912931 | 0.74 | SLC9A1 (0.59) | EEF2KSLC9A1ALDH1A1MEN1NPC1 | |
| SCHEMBL926631 | 0.73 | SLC9A1 (0.43) | EEF2KSLC9A1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |