Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318708 | 0.90 | ALOX15 (0.56) | ALOX15ALOX12HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL13608937 | 0.87 | GRIA1 (0.44) | ALOX15ALOX12HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL28448063 | 0.87 | GRIA1 (0.44) | ALOX15ALOX12HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL1760478 | 0.84 | ALOX15 (0.54) | ALOX15ALOX12HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL11038842 | 0.82 | ESR1 (0.48) | ALOX15ALOX12HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL6254952 | 0.82 | KLF10 (0.43) | ALOX15KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL6040093 | 0.79 | ALOX15 (0.56) | ALOX15ALOX12KDM4EMAPTMEN1 | |
| SCHEMBL5676149 | 0.79 | ALOX15 (0.68) | ALOX15ALOX12KDM4EMAPTMEN1 | |
| SCHEMBL9861549 | 0.77 | HMGCR (0.47) | ALOX15KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL8830418 | 0.76 | KLF10 (0.46) | ALOX15KDM4EMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211328-B1 | IN PRESENCE OF AN ACID | GUN EI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-04-03 | — | — | US | disclosed |