Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 11/20 | 0.54 |
| ▸ | CACNA1A | O00555 | 11/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 11/20 | 0.54 |
| ▸ | CACNG3 | O60359 | 11/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 11/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 11/20 | 0.54 |
| ▸ | CACNB3 | P54284 | 11/20 | 0.54 |
| ▸ | CACNA2D1 | P54289 | 11/20 | 0.54 |
| ▸ | CACNG7 | P62955 | 11/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 11/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 11/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 11/20 | 0.54 |
| ▸ | CACNG1 | Q06432 | 11/20 | 0.54 |
| ▸ | CACNB2 | Q08289 | 11/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 11/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 11/20 | 0.54 |
| ▸ | CACNA1E | Q15878 | 11/20 | 0.54 |
| ▸ | CACNA2D4 | Q7Z3S7 | 11/20 | 0.54 |
| ▸ | CACNA2D3 | Q8IZS8 | 11/20 | 0.54 |
| ▸ | CACNG8 | Q8WXS5 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910360 | 0.83 | PRNP (0.42) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7911213 | 0.75 | CACNB4 (0.37) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7902782 | 0.74 | ALDH1A1 (0.40) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL11626481 | 0.70 | MAPT (0.45) | — | |
| SCHEMBL30593161 | 0.70 | MAPT (0.45) | — | |
| SCHEMBL6501518 | 0.70 | ACHE (0.48) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL9270724 | 0.70 | POLB (0.47) | — | |
| SCHEMBL11628165 | 0.69 | POLB (0.42) | — | |
| SCHEMBL30593158 | 0.69 | POLB (0.42) | — | |
| SCHEMBL11727883 | 0.69 | ALDH1A1 (0.44) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |