Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910622 | 0.93 | HSD17B10 (0.39) | HSD17B10TSHRLMNAKDM4ENPC1 | |
| SCHEMBL7911574 | 0.84 | LMNA (0.43) | HSD17B10TSHRLMNAKDM4ENPC1 | |
| SCHEMBL7917118 | 0.79 | ROCK2 (0.34) | HSD17B10TSHRLMNAKDM4ENPC1 | |
| SCHEMBL7913269 | 0.79 | ROCK2 (0.34) | HSD17B10TSHRLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29922027 | 0.79 | ROCK2 (0.34) | HSD17B10TSHRLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1150210 | 0.79 | ROCK2 (0.34) | HSD17B10TSHRLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7911557 | 0.79 | FFAR1 (0.35) | HSD17B10TSHRLMNAKDM4ENPC1 | |
| SCHEMBL7903245 | 0.79 | SMN1; SMN2 (0.44) | HSD17B10TSHRLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7910547 | 0.79 | HSD17B10 (0.38) | HSD17B10TSHRLMNAKDM4ENPC1 | |
| SCHEMBL7917122 | 0.78 | ROCK2 (0.34) | HSD17B10TSHRLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |