Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
| ▸ | WNT3A | P56704 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387303 | 0.83 | OPRM1 (0.59) | MAOBNPC1RAB9AMAOACTNNB1 | |
| SCHEMBL30417964 | 0.83 | OPRM1 (0.59) | MAOBNPC1RAB9AMAOACTNNB1 | |
| SCHEMBL7901142 | 0.83 | NR4A2 (0.74) | MAOBNR4A2PTPN1ALDH1A1 | |
| SCHEMBL25231300 | 0.81 | CTNNB1 (0.73) | NPC1RAB9ASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL1516344 | 0.80 | NPC1 (0.83) | NPC1RAB9AKDM4ESMN1; SMN2CTNNB1 | |
| SCHEMBL1554690 | 0.80 | CTNNB1 (0.66) | NPC1RAB9AKDM4ESMN1; SMN2CTNNB1 | |
| SCHEMBL11698521 | 0.80 | MAOB (0.71) | MAOBNPC1RAB9AKDM4EMAOA | |
| SCHEMBL11616088 | 0.80 | RAB9A (0.61) | MAOBNPC1RAB9ASMN1; SMN2MAOA | |
| SCHEMBL10878729 | 0.78 | RAB9A (0.65) | MAOBNPC1RAB9ASMN1; SMN2MAOA | |
| SCHEMBL22964154 | 0.78 | CALM1 (0.64) | MAOBNPC1RAB9AMAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |