Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918622 | 0.89 | ADRA2A (0.60) | ADRA2ATAAR1ALDH1A1ADRA2BADRA2C | |
| SCHEMBL7913278 | 0.89 | ADRA2A (0.60) | ADRA2ATAAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL7921652 | 0.87 | TAAR1 (0.57) | ADRA2ATAAR1ALDH1A1MEN1LMNA | |
| SCHEMBL7924900 | 0.85 | TAAR1 (0.55) | ADRA2ATAAR1ALDH1A1MEN1LMNA | |
| SCHEMBL7923351 | 0.84 | ADRA2A (0.60) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL7921654 | 0.84 | TAAR1 (0.54) | ADRA2ATAAR1ALDH1A1MEN1LMNA | |
| SCHEMBL7911111 | 0.81 | TAAR1 (0.65) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL7918363 | 0.80 | TAAR1 (0.51) | ADRA2ATAAR1ALDH1A1MEN1LMNA | |
| SCHEMBL7919840 | 0.80 | TAAR1 (0.51) | ADRA2ATAAR1ALDH1A1MEN1LMNA | |
| SCHEMBL7918614 | 0.80 | TAAR1 (0.51) | ADRA2ATAAR1ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |