Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913278 | 0.87 | ADRA2A (0.60) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL7910877 | 0.84 | ADRA2A (0.62) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL7918622 | 0.83 | ADRA2A (0.60) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL7921652 | 0.81 | TAAR1 (0.57) | ADRA2ATAAR1 | |
| SCHEMBL7911111 | 0.80 | TAAR1 (0.65) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL7924900 | 0.79 | TAAR1 (0.55) | ADRA2ATAAR1 | |
| SCHEMBL7921654 | 0.79 | TAAR1 (0.54) | ADRA2ATAAR1 | |
| SCHEMBL7921649 | 0.76 | ADRA2A (0.56) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL7924152 | 0.75 | ADRA2A (0.72) | ADRA2ATAAR1ADRA2BADRA2CADRA1D | |
| SCHEMBL20152367 | 0.75 | ADRA2A (1.00) | ADRA2ATAAR1ADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |